The series was created by Bob Lowry and features Hank Azaria as Dr. Craig "Huff" Huffstodt, a psychiatrist whose life changes abruptly when a 15-year-old client commits suicide in his office. The series follows Huff, his family, and his friend Russell Tupper, played by Oliver Platt, as they navigate life.
The first season was broadcast on Showtime between November 7, 2004 and January 30, 2005. The second season premiered on April 2, 2006 and ended on June 25, 2006. Two days before the finale, Showtime announced that the show would not be picked up for a third season, and several plotlines, including the resolution of pending criminal charges against Russell Tupper and the possibility of reconciliation between Huff and Beth were left unresolved.
The two-hour pilot episode was filmed in Vancouver, British Columbia. Later, production for Huff was moved to Delfino Stages in Los Angeles, California.